Health
NHS Warns Public to Limit Co-Codamol Use to Three Days

The NHS has issued a critical warning regarding the use of the painkiller co-codamol, urging users to limit their intake to no more than three days. This advisory affects millions in the United Kingdom, where tens of millions of doses are dispensed annually. The NHS cautions that prolonged use could lead to increased tolerance to the active ingredient, codeine, as well as potential addiction.
Co-codamol combines paracetamol and codeine, making it effective for moderate pain relief. According to NHS statistics, pharmacies alone dispense around 650,000 prescriptions for this medication each year, in addition to those provided by general practitioners. While it is available over the counter in low-strength formulations, the NHS emphasizes the importance of adhering to recommended usage guidelines.
Health Risks of Prolonged Use
The NHS warns that users should not take co-codamol for longer than three days without consulting a healthcare professional. If pain persists, individuals are advised to speak with a pharmacist or doctor for alternative treatment options. The advisory notes that extended use can lead to a need for higher doses, which can negatively impact pain management.
The NHS statement highlights the risk of developing hyperalgesia, a condition where individuals may become more sensitive to pain as a result of continued opioid use. This condition necessitates a gradual reduction in dosage, overseen by a healthcare provider, to alleviate symptoms and avoid dependence.
Addiction to codeine is a serious concern, prompting the NHS to recommend that treatment plans be carefully monitored, particularly for those on long-term medication for chronic conditions such as cancer pain. Patients are encouraged to discuss any worries about tolerance or addiction with their doctors.
International Regulations
Co-codamol’s availability varies across the globe due to its codeine content, which is classified as an opioid. In the USA, codeine is categorized as a controlled substance, and co-codamol is not available for purchase over the counter. Similar restrictions are in place in Australia, Canada, and several European countries, reflecting the cautious approach taken by health authorities regarding opioid medications.
In summary, the NHS’s warning serves as an urgent reminder for users of co-codamol to adhere to usage guidelines and consult healthcare professionals if pain persists. This proactive stance aims to mitigate the risks associated with prolonged opioid use and ensure safer pain management practices.
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